FMN2 Products

Description

The FMN2 gene encodes a 1,722 amino acid long, 180 kDA formin-2 protein that is essential in cytoskeletal organization as well as establishment of cell polarity, particularly during female germ cell meiosis. This gene reacts to responses in DNA damage, cellular stress, and hypoxia. Additionally, it protects cells against apoptosis by protecting CDKN1A against degradation. FMN2 participates in dorso-ventral axis formation and interacts with the SPIRE1 gene. It has been associated with infertility, coronary heart disease, multiple sclerosis, atherosclerosis, and aortic aneurysms.

Bioinformatics

Entrez	56776 Human
Uniprot	Q9NZ56 Human AAH14364 Human
Product By Gene ID	56776
Alternate Names	formin 2

Diseases related to FMN2

Discover more about diseases related to FMN2.

Chondrosarcoma
Malignant Neoplasms
Neoplasms
Carcinogenesis
Infertility
Malignant Neoplasm Of Pancreas
Glioblastoma
Melanoma
Parathyroid Neoplasms
Aneuploidy
Carcinoma
Retroviridae Infections
Dwarfism
Neoplasms, Multiple Primary
Meningioma
Congenital Absence
Adenocarcinoma
Microcephaly

Pathways for FMN2

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Meiosis I
Meiosis
Fertilization
Glycosylation
Metaphase
Chromosome Segregation
Localization
Anaphase
Cytokinesis
Cell Division
Limb Morphogenesis
Oogenesis
Tissue Homeostasis
Actin Nucleation

Research Areas for FMN2

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Signal Transduction

PTMs for FMN2

Learn more about PTMs related to FMN2.

Glycosylation

Bioinformatics Tool for FMN2

Discover related pathways, diseases and genes to FMN2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.