Host: Mouse Monoclonal
Host: Rabbit Polyclonal
Haemophilia A is an X-linked, recessive, bleeding disorder caused by a deficiency in the activity of coagulation factor VIII. Affected individuals develop a variable phenotype of haemorrhage into joints and muscles, easy bruising, and prolonged bleeding from wounds. The disorder is caused by heterogeneous mutations in the factor VIII gene. Up to 30% of haemophilia A patients given therapeutic fVIII can make inhibitory antibodies, the majority of which are reactive with its C2 and A2 domains.
|Product By Gene ID
- Procoagulant component
- Antihemophilic factor
- factor VIII F8B
- coagulation factor VIIIc
- F8Ccoagulation factor VIII
- coagulation factor VIII, procoagulant component
Bioinformatics Tool for Factor VIII A2 domain
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