Factor VIII A2 domain Products


Haemophilia A is an X-linked, recessive, bleeding disorder caused by a deficiency in the activity of coagulation factor VIII. Affected individuals develop a variable phenotype of haemorrhage into joints and muscles, easy bruising, and prolonged bleeding from wounds. The disorder is caused by heterogeneous mutations in the factor VIII gene. Up to 30% of haemophilia A patients given therapeutic fVIII can make inhibitory antibodies, the majority of which are reactive with its C2 and A2 domains.


Entrez Human
Uniprot Human
Product By Gene ID 2157
Alternate Names
  • Procoagulant component
  • Antihemophilic factor
  • factor VIII F8B
  • coagulation factor VIIIc
  • DXS1253E
  • F8Ccoagulation factor VIII
  • AHF
  • coagulation factor VIII, procoagulant component

Bioinformatics Tool for Factor VIII A2 domain

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