Ephrin-B Products

Antibodies
Ephrin-B Antibody [Unconjugat ...
Ephrin-B Antibody [Unconjugated]
PPS047
Species: Hu, Mu, Rt, Ch, Xp
Applications: WB
Host: Rabbit Polyclonal
Ephrin-B Antibody [Unconjugat ...
Ephrin-B Antibody [Unconjugated]
PPS048
Species: Hu, Mu, Rt, Ch, Xp
Applications: WB
Host: Rabbit Polyclonal
Ephrin-B Antibody [Unconjugat ...
Ephrin-B Antibody [Unconjugated]
PPS049
Species: Hu, Mu, Rt, Ch, Xp
Applications: WB
Host: Rabbit Polyclonal
Lysates
Ephrin-B Overexpression Lysat ...
Ephrin-B Overexpression Lysate (Na...
NBL1-10146
Applications: WB
Proteins
Ephrin-B Recombinant Protein
Ephrin-B Recombinant Protein
NBP1-72437
Species: Hu
Applications: PAGE

Description

The Ephrin B gene (EPHB6) encodes an ephrin type-B receptor 6 protein that has three isoforms. Isoform 1 is 1,021 amino acids long at 110 kDA while isoform 2 is 744 amino acids long, 81 kDA, and isoform 3 is 540 amino acids long at 57 kDA. Ephrin receptors are critical to various developmental processes especially in the nervous system. The receptor coded by the EPHB6 gene lacks the kinase activity of most receptor tyrosine kinases, thus binds to ephrin-B ligands. EPHB6 is involved in axon guidance, cell adhesion ephrins signaling, MAPK signaling, cytoskeleton remodeling reverse signaling by ephrin B, and endothelin-1 signaling pathway. It is known to interact with genes CRK, CRKL, EFNB2, MLLT4, and SAT1. EPHB6 has been investigated regarding its role in various diseases such as: leukemia, neuroblastoma, breast cancer, astrocytoma, gliosarcoma; familial colorectal cancer, melanoma, prostate carcinoma, and lung cancer.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Mouse
Product By Gene ID 1947
Alternate Names
  • LERK-2
  • ELK-L
  • EFL3
  • ligand of eph-related kinase 2
  • EFL-3
  • MGC8782
  • EPH-related receptor tyrosine kinase ligand 2
  • craniofrontonasal syndrome (craniofrontonasal dysplasia)
  • Elk-L
  • EPLG2CFNS
  • LERK2CFND
  • ELK ligand
  • ephrin-B1

Research Areas for Ephrin-B

Find related products by research area and learn more about each of the different research areas below.

Phospho-Specific

PTMs for Ephrin-B

Learn more about PTMs related to Ephrin-B.

Phosphorylation
Methylation
Cleavage
Dephosphorylation
Ubiquitination

Bioinformatics Tool for Ephrin-B

Discover related pathways, diseases and genes to Ephrin-B. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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