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eIF2 alpha/EIF2S1 Products

Antibodies
eIF2 alpha/EIF2S1 Antibody (O ...
eIF2 alpha/EIF2S1 Antibody (OTI3H4)
Species: Hu, Mu, Rt, Ca, Pm, Pm
Applications: WB, Flow, ICC/IF, IHC
Host: Mouse Monoclonal
Lysates
eIF2 alpha/EIF2S1 Overexpress ...
eIF2 alpha/EIF2S1 Overexpression L...
NBP2-04263
Species: Hu
Applications: WB
Proteins
Recombinant Human eIF2 alpha/ ...
Recombinant Human eIF2 alpha/EIF2S...
NBP1-44467
Species: Hu
Applications: PAGE
eIF2 alpha/EIF2S1 Recombinant ...
eIF2 alpha/EIF2S1 Recombinant Prot...
NBP2-49428PEP
Species: Hu
Applications: AC

Description

EIF2S1, also known as eIF2a, is the alpha subunit of the translation initiation factor eIF2 complex which catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. The phosphorylation state of eIF2S1 controls the rate of tRNA translation. When eIF2a is not phosphorylated, translation occurs at a normal rate. However, upon phosphorylation by one of several kinases, eIF2S1 is stabilized, thus preventing the GDP/GTP exchange reaction and slowing translation. Recombinant human EIF2S1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot
Product By Gene ID 1965
Alternate Names
  • eIF2 alpha
  • EIF2
  • EIF-2
  • EIF2A
  • EIF-2A
  • EIF-2alpha
  • EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
  • EIF2S1

Research Areas for eIF2 alpha/EIF2S1

Find related products by research area and learn more about each of the different research areas below.

Phospho-Specific