Species: Hu, Mu, Bv, Pm, Pm, RM
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Bv, Ca
Applications: ELISA, IHC
Host: Goat Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
The activation of mitogen-activated protein kinase (MAPK) cascades transduces various extracellular signals to the nucleus to induce gene expression, cell proliferation, differentiation, cell cycle arrest, and apoptosis. For full activation of MAPKs, dual-specificity kinases phosphorylate both threonine and tyrosine residues in MAPK TXY motifs. MKPs are dual-specificity phosphatases that dephosphorylate the TXY motif, thereby negatively regulating MAPK activity.[supplied by OMIM]
Bioinformatics
| Entrez |
Mouse
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
80824 |
| Alternate Names |
- dual specificity phosphatase 16
- EC 3.1.3.16
- EC 3.1.3.48
- FLJ36298
- FLJ40991
- KIAA1700MGC129701
- MAP kinase phosphatase 7
- MAPK phosphatase-7
- Mitogen-activated protein kinase phosphatase 7
- MKP7dual specificity protein phosphatase 16
- MKP-7MGC129702
|
