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DMRTC2, or Doublesex- and mab-3-related transcription factor C2, contains a 39 kDa and a 24 kDa isoform, and is broadly associated with sexual development, though its specific function is unknown. Disease research is currently being conducted on the relationship between DMRTC2 and neuronitis. The protein is linked to the regulation of transcription, sex differentiation, and cell differentiation, and has been found to interact with several other proteins, including ABTB1, IRF9, IVNS1ABP, MCM6, and SREBF2.