DHCR7 Products

Antibodies
DHCR7 Antibody
DHCR7 Antibody
H00001717-D01P
Species: Hu, Mu, Rt
Applications: WB, ELISA
Host: Rabbit Polyclonal
DHCR7 Antibody
DHCR7 Antibody
NBP1-80740
Species: Hu, Mouse
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
DHCR7 Overexpression Lysate ( ...
DHCR7 Overexpression Lysate (Denat...
H00001717-T01
Species: Hu
Applications: WB
DHCR7 Overexpression Lysate ( ...
DHCR7 Overexpression Lysate (Native)
NBL1-09858
Applications: WB
DHCR7 Overexpression Lysate ( ...
DHCR7 Overexpression Lysate (Native)
NBP2-10201
Applications: WB
Proteins
DHCR7 Recombinant Protein
DHCR7 Recombinant Protein
H00001717-P01
Species: Hu
Applications: WB, ELISA, PA
DHCR7 Recombinant Protein Ant ...
DHCR7 Recombinant Protein Antigen
NBP1-80740PEP
Species: Hu
Applications: AC
RNAi
DHCR7 RNAi
DHCR7 RNAi
H00001717-R01
Species: Hu

Description

The DHCR7 gene encodes delta-7-sterol reductase (EC 1.3.1.21), the penultimate enzyme of mammalian sterol biosynthesis that converts 7-dehydrocholesterol (7-DHC) to cholesterol. This enzyme removes the C(7-8) double bond introduced by the sterol delta8-delta7 isomerases. In addition, its role in drug-induced malformations is known: inhibitors of the last step of cholesterol biosynthesis such as AY9944 and BM15766 severely impair brain development (Moebius et al., 1998 [PubMed 9465114]).[supplied by OMIM]

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 1717
Alternate Names
  • SLOS
  • EC 1.3.1
  • EC 1.3.1.21
  • D7SR
  • 7-DHC reductase
  • sterol delta-7-reductase
  • Sterol Delta(7)-reductase
  • delta-7-dehydrocholesterol reductase
  • Putative sterol reductase SR-2
  • Smith-Lemli-Opitz syndrome
  • 7-dehydrocholesterol reductase

PTMs for DHCR7

Learn more about PTMs related to DHCR7.

Oxidation
Cleavage
Demethylation
Phosphorylation
Methylation
Prenylation

Bioinformatics Tool for DHCR7

Discover related pathways, diseases and genes to DHCR7. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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