Cytokeratin 5/75 Products

Description

Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors. Cytokeratin 5/75 is expressed in normal basal cells. Mutations of the Cytokeratin 5/75 gene (KRT5) have been shown to result in the autosomal dominant disorder epidermolysis bullosa (EB).

Bioinformatics

Entrez	3852 Human 369017 Rat
Product By Gene ID	3852
Alternate Names	58 kDa cytokeratin CK5 CK-5 Cytokeratin-5 DDD EBS2 epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types K5 keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockaynetypes) keratin 5 keratin, type II cytoskeletal 5 Keratin-5 KRT5A Type-II keratin Kb5

Research Areas for Cytokeratin 5/75

Find related products by research area and learn more about each of the different research areas below.

Cell Biology
Cellular Markers