Species: Hu, Mu, RM
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: ELISA, NULL
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Description
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (heart/muscle isoform) of subunit VIa, and polypeptide 2 is present only in striated muscles. Polypeptide 1 (liver isoform) of subunit VIa is encoded by a different gene, and is found in all non-muscle tissues. These two polypeptides share 66% amino acid sequence identity.
Bioinformatics
| Product By Gene ID |
1339 |
| Alternate Names |
- COX VIa-M
- COX6A
- COX6AH
- COXVIAH
- Cytochrome c oxidase polypeptide VIa-heart
- cytochrome c oxidase subunit 6A2, mitochondrial
- cytochrome c oxidase subunit VIa polypeptide 2
- Cytochrome c oxidase subunit VIA-muscle
|
