Complement C4b Products

Antibodies
Complement C4b Antibody (1F2) ...
Complement C4b Antibody (1F2)
H00000721-M03
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
Complement C4b Antibody
Complement C4b Antibody
NBP1-31229
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Complement C4b Antibody
Complement C4b Antibody
NBP1-50503
Species: Hu
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Proteins
Recombinant Human Complement ...
Recombinant Human Complement C4b P...
H00000721-Q01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human Complement ...
Recombinant Human Complement C4b P...
H00000721-Q02
Species: Hu
Applications: WB, ELISA, PA
RNAi
Complement C4b RNAi
Complement C4b RNAi
H00000721-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

C4b encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Product By Gene ID 721
Alternate Names
  • C4B12
  • EC 2.7.11
  • complement component 4B
  • EC 2.1.1.144
  • C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3
  • complement C4B1a
  • Basic complement C4
  • complement C4-B
  • CH
  • Chido form of C4
  • C4B3
  • basic C4
  • C4B1
  • C4FMGC164979
  • CPAMD3FLJ60561
  • CO4C4B5
  • C4B2
  • complement component 4B (Chido blood group)

Bioinformatics Tool for Complement C4b

Discover related pathways, diseases and genes to Complement C4b. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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