Complement C3c Products

Antibodies
Complement C3c Antibody (10-0 ...
Complement C3c Antibody (10-02A)
NB100-64339
Species: Hu
Applications: WB, ELISA, Flow, IHC, IHC-Fr
Host: Mouse Monoclonal
Complement C3c Antibody (4)
Complement C3c Antibody (4)
NBP1-49651
Species: Hu
Applications: IP
Host: Rat Monoclonal

Description

C3 consists of two polypeptide chains (alpha, molecular weight 115 kDa and beta, molecular weight 75 kDa) and is usually present in serum at 1 to 2 mg/L. It is the pivotal protein of the complement system, being central in the classical pathway and the alternative pathway. It is cleaved by the classical pathway convertase C4b2a and the alternative pathway convertase C3bBb, into C3b and C3a. The C3a peptide is an important anaphylotoxin, whilst the C3b has three main roles: 1. Important opsonin phagocyte cells have C3b receptors. 2. Participates in the amplification loop in the alternative pathway. 3. Complexed with C4b2a this is the C5 convertase which leads ultimately to target cell lysis. C3c, along with iC3b and C3dg, is formed as a result of C3b inactivation by Factor I and various cofactors. The C3 fragments are eliminated by liver phagocytic cells.

Bioinformatics

Entrez Human
Uniprot Human
Product By Gene ID 718
Alternate Names
  • ARMD9
  • complement component C3
  • AHUS5
  • complement C3
  • C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1
  • CPAMD1acylation-stimulating protein cleavage product
  • ASP
  • complement component 3

Research Areas for Complement C3c

Find related products by research area and learn more about each of the different research areas below.

Immunology
Innate Immunity
Neuronal Cell Markers
Neuroscience

Bioinformatics Tool for Complement C3c

Discover related pathways, diseases and genes to Complement C3c. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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