Species: Hu, Bv
Applications: WB, IHC, IHC-P
Host: Rabbit Monoclonal
Collagens are highly conserved throughout evolution and are characterized by an uninterrupted "Glycine X Y" triplet repeat that is a necessary part of the triple helical structure. Type I collagen (95 kDa) is found in bone, cornea, skin and tendon. Mutations in the encoding gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for Platelet derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor.
|Product By Gene ID
- Collagen 1/2/3/4/5
- collagen alpha 1 chain type I
- pro-alpha-1 collagen type 1
- Alpha-1 type I collagen
- collagen of skin, tendon and bone, alpha-1 chain
- collagen alpha-1(I) chain
- collagen, type I, alpha 1
Bioinformatics Tool for Collagen I/II/III/IV/V
Discover related pathways, diseases and genes to Collagen I/II/III/IV/V. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.