Coilin Products

Description

Coilin is encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14.

Bioinformatics

Entrez	12812 Mouse 8161 Human
Uniprot	NM_004645 Human NP_004636 Human NP_004636.1 Human P38432 Human
Product By Gene ID	8161
Alternate Names	CLN80p80-coilin coilin p80 coilin p80

Research Areas for Coilin

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Neuroscience