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CMTM2, also known as CKLF-like MARVEL transmembrane domain-containing protein 2, is a 248 amino acid 27.5 kDa protein commonly found in the membrane as a multi-pass protein. This protein has been shown to be involved in testis development as a member of the chemokine-like factor gene superfamily. The protein has been shown to interact with UBE2A and the Androgen receptor. There has also been research revolving around the CMTM2 proteins involvement in male infertility.
