Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Monoclonal
Species: Hu
Applications: WB, IHC, IP
Host: Rabbit Polyclonal
Species: Hu, Mu
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Rt
Applications: ELISA
Species: Mu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
CHD3 is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD3 is a key component of the NuRD (nucleosomal remodeling) complex and directly interacts with histone deacetylases 1 and 2, ATR, and TRIM 27. Studies in several species suggest a role for CHD3 in the repression of developmental genes.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
1107 |
| Alternate Names |
- ATP-dependent helicase CHD3
- CHD-3
- chromodomain helicase DNA binding protein 3
- chromodomain-helicase-DNA-binding protein 3
- EC 3.6.1
- EC 3.6.4.12
- hZFH
- Mi-2 autoantigen 240 kDa protein
- Mi-2a
- Mi2-alpha
- Mi2-ALPHA
- ZFH
- Zinc finger helicase
- zinc-finger helicase (Snf2-like)
|
