CBX4 Products

Antibodies
CBX4 Antibody
CBX4 Antibody
NBP1-83225
Species: Hu
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
CBX4 Antibody
CBX4 Antibody
H00008535-B01P
Species: Hu
Applications: WB, ELISA
Host: Mouse Polyclonal
Lysates
CBX4 Overexpression Lysate (D ...
CBX4 Overexpression Lysate (Denatu...
H00008535-T01
Species: Hu
Applications: WB
Proteins
CBX4 Recombinant Protein
CBX4 Recombinant Protein
H00008535-P01
Species: Hu
Applications: WB, ELISA, PA
CBX4 Recombinant Protein Anti ...
CBX4 Recombinant Protein Antigen
NBP1-83225PEP
Species: Hu
Applications: AC
RNAi
CBX4 RNAi
CBX4 RNAi
H00008535-R01
Species: Hu

Description

PC2 is the human homolog of the Drosophila 'Polycomb' (Pc) protein which has been identified as a gene family member associated with a cellular memory system that is responsible for the inheritance of gene activity by progeny cells. The human Pc homolog gene is more closely related to a Xenopus Pc homolog, XPc, than to a previously described human Pc homolog, CBX2 (hPc1). However, the hPc2 and CBX2/hPc1 proteins are shown to colocalize in interphase nuclei of human U-2 OS osteosarcoma cells, suggesting that the proteins are part of a common protein complex. The human protein is believed to function as a repressor of proto-oncogene activity and that interference with hPc2 function can lead to derepression of proto-oncogene transcription and subsequently to cellular transformation. Other reports describe PC2 as a protein that has SUMO E3 activity for the corepressors CtBP and CtBP2.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 8535
Alternate Names
  • hPc2
  • chromobox homolog 4 (Drosophila Pc class)
  • Pc2
  • Polycomb 2 homolog
  • Pc class 2 homolog
  • Chromobox protein homolog 4
  • NS5ATP1-binding protein 16
  • hPC2
  • E3 SUMO-protein ligase CBX4
  • PC2
  • Drosophila)
  • chromobox homolog 4

Research Areas for CBX4

Find related products by research area and learn more about each of the different research areas below.

Apoptosis

Bioinformatics Tool for CBX4

Discover related pathways, diseases and genes to CBX4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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