Beta 2 Adaptin Products

Antibodies
Beta 2 Adaptin Antibody
Beta 2 Adaptin Antibody
NBP2-15563
Species: Hu, Mu, Bovine, Porcine, Rat, Zebrafish
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Beta 2 Adaptin Antibody
Beta 2 Adaptin Antibody
NB100-74371
Species: Hu, Mu, Rt, Bv
Applications: WB
Host: Rabbit Polyclonal
Beta 2 Adaptin Antibody (2D5) ...
Beta 2 Adaptin Antibody (2D5)
H00000163-M01
Species: Hu
Applications: WB, ELISA, IHC, IHC-P
Host: Mouse Monoclonal
Lysates
Beta 2 Adaptin Overexpression ...
Beta 2 Adaptin Overexpression Lysa...
NBP2-10970
Applications: WB
Beta 2 Adaptin Overexpression ...
Beta 2 Adaptin Overexpression Lysa...
NBL1-07579
Applications: WB
Beta 2 Adaptin Overexpression ...
Beta 2 Adaptin Overexpression Lysa...
NBP2-11335
Applications: WB
Proteins
Beta 2 Adaptin Partial Recomb ...
Beta 2 Adaptin Partial Recombinant...
H00000163-Q01
Species: Hu
Applications: WB, ELISA, PA
Beta 2 Adaptin Recombinant Pr ...
Beta 2 Adaptin Recombinant Protein
H00000163-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
Beta 2 Adaptin RNAi
Beta 2 Adaptin RNAi
H00000163-R01
Species: Hu
Beta 2 Adaptin RNAi
Beta 2 Adaptin RNAi
H00000163-R02
Species: Hu

Description

Clathrin-mediated endocytosis is the pathway by which many receptors for nutrients and hormones are internalized to be recycled or down-regulated. During formation of clathrin coated membranes, clathrin co-assembles with heterotetrameric molecules known as assembly polypeptides (APs) or adaptors which form a layer of protein coat between the clathrin lattice and the membrane. There are two characterized adaptors AP1 and AP2. AP1 is associated with clathrin coated vesicles at the trans-Golgi network and AP2 is associated with the endocytic clathrin coated vesicles at the plasma membrane and has been shown to specifically interact with Shc and EGF receptor. AP2 is composed of four subunits, two separate 100 kDa gene products with similar domain structures (alpha and beta adaptin) and a 50 and 17 kDa subunit. There are two alpha-adaptin genes, alpha A and alpha C which have a tissue specific pattern of expression.

Bioinformatics

Entrez Human
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 163
Alternate Names
  • AP2-BETA
  • Beta-adaptin
  • AP105B
  • Beta-2-adaptin
  • Plasma membrane adaptor HA2/AP2 adaptin beta subunit
  • clathrin-associated/assembly/adaptor protein, large, beta 1
  • Clathrin assembly protein complex 2 beta large chain
  • beta-adaptin
  • Adaptor protein complex AP-2 subunit beta
  • beta-2-adaptin
  • Adapter-related protein complex 2 beta subunit
  • CLAPB1AP-2 complex subunit beta
  • ADTB2adaptin, beta 2 (beta)
  • DKFZp781K0743
  • adaptor-related protein complex 2, beta 1 subunit

Diseases related to Beta 2 Adaptin

Discover more about diseases related to Beta 2 Adaptin.

Malignant Neoplasms
Stomach Neoplasms
Malignant Neoplasm Of Stomach
Ear Inflammation
Malignant Neoplasm Of Ovary
Otitis Media
Ovarian Neoplasm

Pathways for Beta 2 Adaptin

View related products by pathway and learn more about each of the pathways below.

Cell Junction Assembly
Cell Proliferation
Integrin-mediated Signaling Pathway
Epithelial Cell Proliferation
Regulation Of Epithelial Cell Proliferation

Bioinformatics Tool for Beta 2 Adaptin

Discover related pathways, diseases and genes to Beta 2 Adaptin. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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