BAFF Receptor Products


B cell-activating factor receptor (BAFF-R) is a 19 kD type III membrane protein. It belongs to TNFR superfamily, also known as TNFRSF member 13C (TNFRSF13C), BAFF receptor 3 (BR3), or CD268. BAFF-R is expressed on mature B cells, B cell lymphoma, and T cell subset. BAFF-R is the major receptor for BAFF/BLys (or TALL-1, THANK) which binds to TACI and BCMA as well. The interaction of BAFF with BAFF-R promotes NF-234; B activation and plays predominant roles in B-cell maturation and survival as well as costimulates T cell activation and proliferation. TRAF3 is a BAFF-R intracellularly associated protein, which negatively regulates BAFF-R-mediated NF-234; B activation.


Entrez Human
Uniprot Human
Product By Gene ID 115650
Alternate Names
  • BLyS receptor 3
  • CD268 antigen
  • BAFF receptor
  • BR3
  • B-cell-activating factor receptor
  • tumor necrosis factor receptor superfamily member 13C
  • BAFF-R
  • B cell-activating factor receptor
  • CD268
  • BAFFRMGC138235
  • CVID4
  • tumor necrosis factor receptor superfamily, member 13C

Research Areas for BAFF Receptor

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Biologically Active Proteins
Cytokine Research
Lipid and Metabolism

PTMs for BAFF Receptor

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Bioinformatics Tool for BAFF Receptor

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