ATP Citrate Lyase Products

Antibodies
ATP Citrate Lyase Antibody (5 ...
ATP Citrate Lyase Antibody (5F8D11)
NBP2-37429
Species: Hu, Mu, Rt, Mk
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
ATP Citrate Lyase Antibody (3 ...
ATP Citrate Lyase Antibody (3G8)
Species: Hu, Mk
Applications: WB, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
ATP Citrate Lyase Antibody
ATP Citrate Lyase Antibody
NBP1-90266
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
ATP Citrate Lyase Overexpress ...
ATP Citrate Lyase Overexpression L...
NBL1-07240
Applications: WB
Proteins
ATP Citrate Lyase Recombinant ...
ATP Citrate Lyase Recombinant Prot...
NBP1-90267PEP
Species: Hu
Applications: AC
ATP Citrate Lyase Recombinant ...
ATP Citrate Lyase Recombinant Prot...
NBP1-90269PEP
Species: Hu
Applications: AC
ATP Citrate Lyase Recombinant ...
ATP Citrate Lyase Recombinant Prot...
NBP1-90268PEP
Species: Hu
Applications: AC
RNAi
ATP Citrate Lyase RNAi
ATP Citrate Lyase RNAi
H00000047-R02
Species: Hu
ATP Citrate Lyase RNAi
ATP Citrate Lyase RNAi
H00000047-R01
Species: Hu

Description

ATP citrate lyase (ACLY), also known as ATP citrate synthase, is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer of four identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. One of these products, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. NDPK has been found to phosphorylate ACLY and insulin to increase phosphorylation of ACLY (2).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Product By Gene ID 47
Alternate Names
  • ATP-citrate synthase
  • Citrate cleavage enzyme
  • ATP citrate synthase
  • CLATP
  • ATPCL
  • ACLEC 2.3.3.8
  • ATP-citrate (pro-S-)-lyase
  • ATP citrate lyase

Research Areas for ATP Citrate Lyase

Find related products by research area and learn more about each of the different research areas below.

Phospho-Specific

PTMs for ATP Citrate Lyase

Learn more about PTMs related to ATP Citrate Lyase.

Phosphorylation
Oxidation
Carboxylation
Cleavage

Bioinformatics Tool for ATP Citrate Lyase

Discover related pathways, diseases and genes to ATP Citrate Lyase. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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