Ataxin 7 Products

Ataxin 7 Antibody
Ataxin 7 Antibody
Species: Hu, Equine, Porcine, Rabbit
Applications: WB, IP (-)
Host: Rabbit Polyclonal
Ataxin 7 RNAi
Ataxin 7 RNAi
Species: Hu


The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. This locus has been mapped to chromosome 3, and it has been determined that the diseased allele associated with Spinocerebellar ataxia-7, contains 38-130 CAG repeats (near the N-terminus), compared to 7-17 in the normal allele. The exact function of this gene is not known, however, since the encoded protein contains a nuclear localization sequence, and is found to be localized in the nucleus, it has been postulated to be a potential transcription factor. Alternative splicing, resulting in transcript variants encoding different isoforms, has been noted for this gene. (provided by RefSeq)


Entrez Human
Uniprot Human
Product By Gene ID 6314
Alternate Names
  • SCA7
  • FLJ17787
  • ataxin 7

Pathways for Ataxin 7

View related products by pathway and learn more about each of the pathways below.

Histone Acetylation
Cell Division
Cell Migration
Cell Death
Dna Repair

PTMs for Ataxin 7

Learn more about PTMs related to Ataxin 7.


Bioinformatics Tool for Ataxin 7

Discover related pathways, diseases and genes to Ataxin 7. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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