ARF1 Products

Description

The ADP-ribosylation factor (Arf) family comprises a group of structurally and functionally conserved 21 kDa proteins, which are members of the Ras superfamily of regulatory GTP-binding proteins. Arf is involved in intracellular protein traffic to and within the Golgi complex. Arf has a number of disparate activities including maintenance of organelle integrity, assembly of coat proteins, as a co-factor for cholera toxin and as an activator of phospholipase D. The Arf family is divided functionally into the Arf and the Arf-like (Arl) proteins. Arfs share more than 60% sequence identity, appear to be ubiquitous in eukaryotes, and are highly conserved evolutionarily.

Bioinformatics

Entrez	11840 Mouse 375 Human 64310 Rat
Uniprot	AAH11358 Human NM_001024226 Human NP_001019398 Human NP_001019399 Human NP_001649 Human P61204 Human P84077 Human
Product By Gene ID	375
Alternate Names	ADP-ribosylation factor 1

Related ARF1 Blog Posts

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Arf1: A New Focus In Cancer Drug Therapy ARF1 (ADP-ribosylation factor 1) is a protein in the ARF gene family that is responsible for vesicular trafficking within the cell through its activation of phospholipase D. It is found in the cells golgi apparatus and its main function is intra-Golgi...    Read more.

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