AMOT Products

Description

AMOT belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]

Bioinformatics

Entrez	154796 Human
Uniprot	NP_001106962.1 Human Q4VCS5 Human NP_573572 Human NP_573572.1 Human
Product By Gene ID	154796
Alternate Names	angiomotin p80 isoform KIAA1071angiomotin p130 isoform angiomotin

Diseases related to AMOT

Discover more about diseases related to AMOT.

Tumor Angiogenesis
Neoplasms
Pathologic Neovascularization
Malignant Neoplasms
Malignant Neoplasm Of Breast
Cell Invasion
Neoplasm Metastasis
Carcinoma
Cell Transformation, Neoplastic
Hyperplasia
Overlying Behavior
Diabetic Nephropathy
Neoplasms, Experimental
Glioma
Neoplasm Invasiveness
Malignant Neoplasm Of Lung
Degenerative Polyarthritis
Osteosarcoma
Fibrosis

Pathways for AMOT

View related products by pathway and learn more about each of the pathways below.

Angiogenesis
Cell Migration
Localization
Endothelial Cell Migration
Cell Motility
Tube Formation
Gastrulation
Cell Growth
Contact Inhibition
Endoderm Formation
Sprouting Angiogenesis
Cell Proliferation
Gene Silencing
Regulation Of Rho Gtpase Activity
Immune Response
Endocytic Recycling
Vasculogenesis
Epiboly
Chemotaxis
Reverse Transcription

PTMs for AMOT

Learn more about PTMs related to AMOT.

Phosphorylation

Bioinformatics Tool for AMOT

Discover related pathways, diseases and genes to AMOT. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.