alpha Endosulfine Products

Antibodies
alpha Endosulfine Antibody
alpha Endosulfine Antibody
NBP2-13963
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
alpha Endosulfine Antibody (1 ...
alpha Endosulfine Antibody (1H7)
H00002029-M02
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
alpha Endosulfine Antibody
alpha Endosulfine Antibody
NBP1-57010
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Lysates
alpha Endosulfine Knockout 29 ...
alpha Endosulfine Knockout 293T Ce...
NBP2-65495
Species: Hu
Applications: WB
alpha Endosulfine Overexpress ...
alpha Endosulfine Overexpression L...
NBP2-04512
Species: Hu
Applications: WB
alpha Endosulfine Overexpress ...
alpha Endosulfine Overexpression L...
NBL1-10279
Species: Hu
Applications: WB
Proteins
alpha Endosulfine Recombinant ...
alpha Endosulfine Recombinant Prot...
NBP2-13963PEP
Species: Hu
Applications: AC
Recombinant Human alpha Endos ...
Recombinant Human alpha Endosulfin...
NBP1-37076
Species: Hu
Applications: PAGE

Description

alpha Endosulfine is encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. alpha Endosulfine is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 2029
Alternate Names
  • alpha-endosulfine
  • MGC8394
  • MGC78563
  • ARPP-19eMGC4319
  • endosulfine alpha

Research Areas for alpha Endosulfine

Find related products by research area and learn more about each of the different research areas below.

Neuroscience

PTMs for alpha Endosulfine

Learn more about PTMs related to alpha Endosulfine.

Phosphorylation
Methylation
Dephosphorylation

Bioinformatics Tool for alpha Endosulfine

Discover related pathways, diseases and genes to alpha Endosulfine. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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