ALDH8A1 Products

Description

ALDH8A1 belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]

Bioinformatics

Uniprot	Q9H2A2 Human
Product By Gene ID	64577
Alternate Names	Aldehyde dehydrogenase 12 aldehyde dehydrogenase 8 family, member A1 aldehyde dehydrogenase family protein ALDH12aldehyde dehydrogenase family 8 member A1 DJ352A20.2 DKFZp779D2315 EC 1.2.1 EC 1.2.1.- EC 1.2.1.3 MGC138650