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AKT2/3 Products


Description

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. [provided by RefSeq]

Bioinformatics

Uniprot
P31751
Product By Gene ID 208
Alternate Names
  • EC 2.7.11
  • EC 2.7.11.1
  • Murine thymoma viral (v-akt) homolog-2
  • PKB beta
  • PKBB
  • PKBBETA
  • PRKBB
  • Protein kinase Akt-2
  • Protein kinase B beta
  • rac protein kinase beta
  • RAC-beta serine/threonine-protein kinase
  • RAC-BETA
  • RAC-PK-beta
  • v-akt murine thymoma viral oncogene homolog 2

Research Areas for AKT2/3

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Hypoxia
mTOR Pathway
Protein Kinase
Signal Transduction