Hu, Mu, RtApplications:
WB, ELISA, ICC/IF, IHC, IHC-PHost:
Host: Rabbit Polyclonal
Applications: IHC, IHC-P, PEP-ELISA
Host: Goat Polyclonal
Applications: RNAi, RNAi SP
The Adenosine A2b Receptor (ADORA2B) gene codes for a receptor located on chromosome 17 (near the Smith-Magenis syndrome region) that initiates adenylyl cyclase in the presence of adenosine. The encoded adenoside receptor is 332 amino acids long, around 36 kDA, and is member to the G protein-coupled receptor superfamily and interacts with netrin-1 to promote axon elongation. ADORA2B has been associated with cholera, hepatitis B, breast cancer, carcinoma, eclampsia, ischemia, asthma, cystic fibrosis, astrocytoma, and atherosclerosis. It is involved in signal transduction IP3 signaling, GPCR ligand binding and signaling, and the methotrexate pathway through interactions with the EZR, NTN1, ADA, DDC, and SLC9A3R2 genes.
Research Areas for Adenosine A2b R
Find related products by research area and learn more about each of the different research areas below.GPCR
PTMs for Adenosine A2b R
Learn more about PTMs related to Adenosine A2b R.Methylation
Bioinformatics Tool for Adenosine A2b R
Discover related pathways, diseases and genes to Adenosine A2b R. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.