Caspase 9 (CASP9) is a member of the cysteine-aspartic acid protease (caspase) family that is involved in the execution-phase of cell apoptosis. Caspase 9 is expressed as an inactive proenzyme which then undergos proteolytic processing by upstream caspases, to form an active (cleaved) caspase 9 form.
There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Caspase 3 is considered an initiator, as initiated caspase-9 goes on to cleave the effector procaspase-3 and procaspase-7.
Caspase 9 antibodies are important tools for apoptosis studies and research on the caspase family mediated apoptosis signaling pathway.
|Product By Gene ID
- EC 126.96.36.199
- Apoptotic protease-activating factor 3
- Apoptotic protease Mch-6
- apoptotic protease activating factor 3
- MCH6apoptosis-related cysteine protease
- ICE-like apoptotic protease 6
- caspase 9, apoptosis-related cysteine peptidase
Research Areas for active/cleaved Caspase 9
Find related products by research area and learn more about each of the different research areas below.ApoptosisCancerCaspasesCell Biology
Bioinformatics Tool for active/cleaved Caspase 9
Discover related pathways, diseases and genes to active/cleaved Caspase 9. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.