active/cleaved Caspase-3 Products

Kits
active/cleaved Caspase-3 Assa ...
active/cleaved Caspase-3 Assay Kit...
NBP2-54869
Species: Hu, Mu, Rt, Ma
Applications: Flow
Conjugate Catalog # Availability Size Price
active/cleaved Caspase-3 Assa ...
active/cleaved Caspase-3 Assay Kit...
NBP2-54861
Species: Hu, Mu, Rt, Ma
Applications: Flow
Conjugate Catalog # Availability Size Price

Description

Caspase 3 (CASP3) is a member of the cysteine-aspartic acid protease (caspase) family that is involved in the execution-phase of cell apoptosis.

There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Caspase 3 is considered an effector, as it is activated in the apoptotic cell both by extrinsic (death ligand) and intrinsic (mitochondrial) pathways. Specifically, procaspase is activated when the procaspase is cleaved at a particular residue. Activated Caspase 3 then cleaves numerous substrates to effect the morphological changes associated with apoptosis.

Caspase 3 antibodies are important tools for apoptosis studies and research on the caspase family mediated apoptosis signaling pathway.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Product By Gene ID 836
Alternate Names
  • EC 3.4.22
  • CPP-32
  • Apopain
  • CASP-3
  • procaspase3
  • Protein Yama
  • PARP cleavage protease
  • Cysteine protease CPP32
  • caspase-3
  • apoptosis-related cysteine protease
  • Yama
  • EC 3.4.22.56
  • CPP32B
  • CPP32SREBP cleavage activity 1
  • SCA-1
  • caspase 3, apoptosis-related cysteine peptidase

Research Areas for active/cleaved Caspase-3

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Caspases

Bioinformatics Tool for active/cleaved Caspase-3

Discover related pathways, diseases and genes to active/cleaved Caspase-3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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