Apoptosis Pathway

Apoptosis is a programmed cell death mechanism characterized by depolymerization of cytoskeleton, cell shrinkage, chromatin condensation, nuclear fragmentation and translocation of phosphatidylserine to the cell surface. Apoptosis arises from a number of stimuli that initiate multiple signaling pathways which lead to caspase cascade activation and cell death. Apoptosis prevents damaged cells from consuming essential nutrients and spreading infection. Increases in apoptotic activity are hallmarks of several disease states including AIDS, neurodegenerative disorders, insulin-dependent diabetes, myocardial infarction and atherosclerosis.

apoptosis pathway

Explore Your Pathways With Novus Explorer! This free bioinformatics tool is designed to facilitate scientific exploration of related genes, diseases and pathways based on co-citations.

Novus Biologicals offers a variety of top quality antibodies and proteins for apoptosis signaling research such as caspases, p53 pathway, death receptor pathway, mitochondria-mediated pathway, and various inhibitors, inducers, and detection kits etc. Some of our most popular apoptosis research products are included below. Please follow the protein name links for more details.

Apoptosis Signaling Pathway Proteins