MAP2 Antibody

Species: Mu Applications: IHC-P, ICC, WB, IHC Clonality: Polyclonal	Gene: MAP2 Purity: Affinity purified Host: Chicken
Specificity: MAP-2
See All MAP2 Products See All MAP2 Related Products: Lysates Peptides and Proteins Primary Antibodies

Immunogen:	Chickens were immunized with two synthetic peptide / keyhole limpet hemocyanin (KLH) conjugates. These synthetic peptides corresponded to different regions of the MAP-2 gene product, but are shared between the human (NP_002365, NCBI) and mouse (P20357, NCBI) sequences.

	17756 (Mouse)
Related Genes:	MTAP2, METAP2, MAPT, CSNK1E, GFAP, SGSM3, SYP, NES, MTAP1B, MAP1B, MOAP1, MAP1, CA1, CAR1, NGF, NEU1, MAN2A1, BDNF, MBP, KNG1, CALM2, CALM3, CALM1, VIM, FGF2, TH, EGF, NEUN, ENO2, CAR3, CA3, CARS, MAPK3, MAPK1, MAP1A, MTAP4, MAP4, APP, CASP3, MTAP1A

Microtubules are 25nm diameter protein rods found in most kinds of eukarytic cells. They are polymerized from a dimeric subunit made of one a subunit and one b tubulin subunit. Microtubules are associated with a family of proteins called microtubule associated proteins (MAPs), which includes the protein t (tau) and a group of proteins referred to as MAP1, MAP2, MAP3, MAP4 and MAP5. MAP2 is made up of two approx. 280kDa apparent molecular weight bands referred to as MAP2a and MAP2b. A third lower molecular weight form, usually called MAP2c, corresponds to a pair of protein bands running at approx. 70kDa on SDS-PAGE gels. Antibodies to MAP2 are excellent markers on neuronal cells, their perikarya and neuronal dendrites. In contrast t (tau) is found predominantly in neuronal axons. Dendrite specific MAP is found specifically in the dendritic branching of neurons.

Reactivity:	Cross reacts with Mouse.

Uses:	Immunohistochemistry and immunocytochemistry using 2% paraformaldehyde-fixed tissues or cell and western blots.
Dilutions:	immunohistochemistry 1:1000-1:2000, Western Blot 1:1000-1:5000, Immunocytochemistry 1:1000-1:2000, Immunohistochemistry-Paraffin 1:1000-1:2000
Concentrations:	0.1 mg/ml

Buffer:	PBS pH 7.2
Storage:	Store at 4C. Do not freeze.
Preservative:	Sodium Azide
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.