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The CAS9 DNA-cutter is a unique enzyme that is the primary core of an intrinsic DNA editing system found in bacteria. This primitive immune system is used by bacteria to kill and neutralize attacking viruses and confer resistance to bacteriophages. There exist distinct features within most bacterial genomes...

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FOXO1 belongs to the very large Forkhead family of transcription factors which contain a conserved distinct DNA-binding domain known as the Forkhead Box, or FOX. The Forkhead domain is a 100 amino acid long motif capable of binding and bending DNA, and is also known as a “winged helix”. Forkhead family members are involved in a very diverse and wide range of physiological...

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