7500 Conjugated Antibodies
20% Off Selected Lysates

BLOGS


Autophagy is an important cellular process involved in degradation and recycling of cellular macromolecules in response to stress or starvation. Autophagy is carried out in four main phases: phagophore nucleation, autophagosome elongation, docking and fusion with a lysosome, and vesicle breakdown and degradation. ULK1, also known as UNC51-like autophagy activating kinase 1, is a 112 kDa...

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S6K is a serine/threonine kinase that is a member of the ribosomal S6 kinase (RSK) family. S6K exists in two main isoforms, S6K1 and S6K2, which can also be alternatively spliced to produce different splice forms. S6K1 has two major splicing products that are approximately 70 kDa and 85 kDa, known as p70S6K and p85S6K respectively. S6K is activated via phosphorylation by mTORC1 which...

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