LDL Receptor Recombinant Protein

Protein Type: Full length Protein Species: Hu Applications: WB, ELISA	Gene: LDLR
Specificity: LDLR( AAH14514, 1 a.a. - 861 a.a.) full-length recombinant protein with GST.
See All LDL Receptor Products See All LDL Receptor Related Products: Lysates Peptides and Proteins Primary Antibodies RNAi

Entrez:	3949 (Human)
Swiss Prot:	AAH14514.1 (Human)
Related Genes:	APOB, APOE, CFH, FH, APOBEC4, CD320, FH1, LRP1, HMGCR, SREBF2, LPL, PCSK9, LPA, SREBF1, RPSA, 4932441K18RIK, PTPRA, MVP, TNF, INS, APOA1, VLDLR, SCARB1, FTH1, TG, MYBPC3, CETP, LIPC, GH, CD55, CYP7A1, VANGL2, SEPSECS, HAPLN1, NOTO, TRY5, CD36, LRPAP1, LRP2, TOM1L2

The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. LDLR( AAH14514, 1 a.a. - 861 a.a.) full-length recombinant protein with GST.

Reactivity:	Human

Uses:	Western blot, ELISA. Other unit sizes are available. This protein has not been tested for any functionality. Full length proteins may or may not have enzymatic activity. Any customer feedback on functionality would be greatly appreciated.
Dilutions:	ELISA, Western Blot
Unit Size:	10ug (also available: 2ug)

This product is produced by and distributed for Abnova, a company based in Taiwan.

Buffer:	Tris-HCI + Glutathione, pH=8.0
Storage:	Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.