AKT1 [p Ser473] Antibody (EP2109Y) (NB100-79891)

AKT1 [p Ser473] Antibody (EP2109Y) (NB100-79891) (0.1 ml)

Additional Products Available View our AKT1 products. Call 303-730-1950 for recommended products	Ordering Information:
	Catalog Number	NB100-79891
	Size(s)	0.1 ml	Price:
	Availability
Why Choose Novus?	Bulk Quote
	View All AKT1 Primary Antibodies

anti-RAC-PK-alpha antibody, anti-EC 2.7.11 antibody, anti-Proto-oncogene c-Akt antibody, anti-RAC-alpha serine/threonine-protein kinase antibody, anti-Protein kinase B antibody, anti-rac protein kinase alpha antibody, anti-PRKBA antibody, anti-RAC-ALPHA antibody, anti-AKT antibody, anti-RACPKB-ALPHA antibody, anti-PKBMGC99656 antibody, anti-EC 2.7.11.1 antibody, anti-v-akt murine thymoma viral oncogene homolog 1 antibody

AKT1 [p Ser473] Antibody (EP2109Y) Summary:

Species:	Hu, Mu, Rt(-)	Gene:	AKT1
Applications:	WB, ICC, IHC-P	Purity:	IgG purified
Clonality:	Monoclonal	Host:	Rabbit
Specificity:	The antibody detects Akt1 phosphorylated at Serine 473.
Publications:	NB100-79891 has been mentioned in at least 4 Publications

View Additional AKT1 Products

Antibody Pairs	ELISA Kits
Lysates	Peptides and Proteins
Primary Antibodies	RNAi
» View All AKT1 Related Products

AKT1 [p Ser473] Antibody (EP2109Y) Details:

Clone:	EP2109Y
Isotype:	IgG
Immunogen:	A phospho specific peptide corresponding to residues surrounding Ser473 of human Akt1 was used as immunogen.
Modification:	p Ser473

Species Reactivity:

Mouse cross reactivity tested by western blot and IHC. Rat cross reactivity tested by western blot only.

Applications:

Uses:	This product is useful for: Western Blot, Immunohistochemistry-Paraffin, Immunocytochemistry. In Western blot this antibody detects a band at approximately 60kDa.
Dilutions:	Western Blot 1:1000-10000, Immunohistochemistry-Paraffin 1:100-250, Immunocytochemistry 1:100-250
MW:	56 kDa
Unit Size:	0.1 ml
Concentration:	Please see the vial label for concentration.

Packaging:

Storage:	Store at -20°C. Avoid freeze-thaw cycles.
Buffer:	50mM Tris-Glycine [pH 7.4] 0.15M NaCl, 40% Glycerol and 0.05% BSA
Preservative:	0.01% Sodium Azide
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.

Gene Symbol: AKT1

Entrez:	207 (Human)
Entrez:	11651 (Mouse)
Uniprot:	P31749 (Human)

Related Genes:

Background:

Akt1/PKBa is a Ser/Thr protein kinase whose kinase activity plays a key role in various cellular functions, including apoptosis, glycogen synthesis, and cell growth . Akt1/PKBa is activated by various growth and survival factors (1). Phosphorylation on Thr308, Ser473 and Tyr474 is required for full activity. Akt1/PKBa inhibits apoptosis by phosphorylating and inactivating several targets, including caspase-9 (2). Akt1/PKBa regulates glycogen synthesis by phosphorylating and inactivating glycogen synthase kinase-3a and b (3,4). Three mammalian Akt1/PKBa isoforms have been identified.