ACE antibody

Mouse Monoclonal anti-ACE (9B9)

Catalog Number: NB110-68278	Price: $295.00

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Background:

ACE converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilatator. ACE exists in two forms, a 170KD somatic form and a 90KD germinal form. The somatic form is expressed by endothelial cells (especially those of lung capillaries and arterioles), epithelial cells (especially in proximal renal tubules and small intestine), by some neuronal cells and variably by some macrophages and T lymphocytes. The germinal form is expressed by spermatozoa.

Alternate Names:

Anti-ACE 1 antibody, Anti-ACE antibody, Anti-ACE T antibody, Anti-ACE1 antibody, Anti-Angiotensin converting enzyme somatic isoform antibody, Anti-Angiotensin converting enzyme testis specific isoform antibody, Anti-Angiotensin I converting enzyme antibody, Anti-Angiotensin I converting enzyme 1 antibody, Anti-Carboxycathepsin antibody, Anti-CD 143 antibody, Anti-CD143 antibody, Anti-CD143 antigen antibody, Anti-DCP 1 antibody, Anti-DCP antibody, Anti-DCP1 antibody, Anti-Dipeptidyl carboxypeptidase 1 antibody, Anti-Kininase II antibody, Anti-MGC26566 antibody, Anti-Peptidase P antibody, Anti-Peptidyl dipeptidase A antibody, Anti-Testicular ECA antibody

Host:

Mouse

Immunogen:

Human lung ACE

Clone:

9B9

Specificity:

ACE, no cross reactivity with testicular ACE.

Species Reactivity:

This antibody is reactive against Human and Rat. Not yet tested in other species.
Other species have not been tested.

Uses:

This antibody is useful for IHC for frozen sections.
Other applications have not been tested.

Dilutions:

Suggested working dilutions *
Immunohistochemistry-Frozen 1:500,

* Investigator should determine optimal working dilutions.

Packaging:

0.05 ml Affinity purified Mouse ascites.

Concentration:

0.2 mg/ml

Buffer:

PBS, pH 7.4 containing 1% BSA

Preservative:

0.05 % sodium azide

Storage:

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Limitations:

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 6 months from date of receipt.

General References:

1. Mizuiri, S. et al. A. J. Kidney Diseases. 1998; 31 (2): 301-307

Gene Id:

1636

Gene System:

ACE

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