ACTL6A antibody

Mouse Monoclonal anti-ACTL6A - actin-like 6A (3C4)

Catalog Number: H00000086-M10	Price: $295.00

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Background:

This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described.

Alternate Names:

anti-ACTL6 antibody, anti-BAF53A antibody, anti-MGC5382 antibody

Host:

Mouse

Immunogen:

ACTL6A (NP_817126, 1 a.a. ~ 81 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone:

3C4

Isotype:

IgG1 Kappa

Epitope:

MVVERDDGSTLMEIDGDKGKQGGPTYYIDTNALRVPRENMEAISPLKNGMVEDWDSFQAILDHTYKMHVKSEASLHPVLM*

Species Reactivity:

Human.
Other species have not been tested.

Uses:

Antibody Reactive Against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.
Other applications have not been tested.

Dilutions:

Suggested working dilutions *
ELISA,
Western Blot 1:500
* Investigator should determine optimal working dilutions.

Packaging:

0.1 mg IgG purified Mouse ascites.

Buffer:

In 1x PBS, pH 7.2

Preservative:

No Preservative

Storage:

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Limitations:

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 6 months from date of receipt.

Notes:

This antibody is available only in North America and is supplied by Abnova If in stock in Taiwan. delivery is 10-14 days. If not in stock. lead times can be extended. We will inform you of any extended delays within 48 hours. The immunizing protein is also available for this product. Unit cost for the protein is $ 250 (2 ug). $ 305 (10 ug). and $ 445 (25 ug).

Gene Id:

86

Gene System:

ACTL6A

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