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Tripeptidyl-Peptidase I/TPP1 Antibody

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Product Details

Summary
Product Discontinued
View other related Tripeptidyl-Peptidase I/TPP1 Primary Antibodies

Order Details


    • Catalog Number
      H00001200-D01
    • Availability
      Product Discontinued

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Tripeptidyl-Peptidase I/TPP1 Antibody Summary

Immunogen
TPP1 (NP_000382.3, 1 a.a. ~ 563 a.a) full-length human protein.
Clonality
Polyclonal
Host
Rabbit
Gene
TPP1
Purity
Unpurified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunoprecipitation
  • Western Blot
Application Notes
This antibody is useful for Western Blot, Immunoprecipitation, Functional

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
No additive
Preservative
No Preservative
Purity
Unpurified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Tripeptidyl-Peptidase I/TPP1 Antibody

  • Cell growth-inhibiting gene 1 protein
  • ceroid-lipofuscinosis, neuronal 2, late infantile (Jansky-Bielschowsky disease)
  • CLN2
  • CLN2EC 3.4.14.9
  • growth-inhibiting protein 1
  • LINCL
  • LPIC
  • lysosomal pepstatin insensitive protease
  • Lysosomal pepstatin-insensitive protease
  • MGC21297
  • TPP1
  • TPP-1
  • TPP-I
  • Tripeptidyl aminopeptidase
  • tripeptidyl peptidase I
  • tripeptidyl-peptidase 1
  • TripeptidylPeptidase I
  • Tripeptidyl-Peptidase I

Background

TPP1 encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Tripeptidyl-Peptidase
H00001200-D01
Tripeptidyl-Peptidase I/TPP1 Antibody
Species: Hu
Applications: WB, ELISA, IP

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Bioinformatics

Gene Symbol TPP1
Uniprot