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Tripeptidyl-Peptidase I/TPP1 Antibody Pair

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      H00001200-AP51
    • Availability
      Product Discontinued

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Tripeptidyl-Peptidase I/TPP1 Antibody Pair Summary

Description
This antibody pair was tested using a Mammalian Overexpression Lysate.
Specificity
This product is specific for Human TPP1 (Human) Matched Antibody Pair [Gene ID: 1200].
Standard Curve Range
729x to 3x dilution
Assay Type
Sandwich ELISA
Gene
TPP1
Purity
Immunogen affinity purified

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
This antibody pair set comes with matched antibody pair to detect and quantify protein level of human TPP1.

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Preservative
No Preservative
Purity
Immunogen affinity purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Tripeptidyl-Peptidase I/TPP1 Antibody Pair

  • Cell growth-inhibiting gene 1 protein
  • ceroid-lipofuscinosis, neuronal 2, late infantile (Jansky-Bielschowsky disease)
  • CLN2
  • CLN2EC 3.4.14.9
  • growth-inhibiting protein 1
  • LINCL
  • LPIC
  • lysosomal pepstatin insensitive protease
  • Lysosomal pepstatin-insensitive protease
  • MGC21297
  • TPP1
  • TPP-1
  • TPP-I
  • Tripeptidyl aminopeptidase
  • tripeptidyl peptidase I
  • tripeptidyl-peptidase 1
  • TripeptidylPeptidase I
  • Tripeptidyl-Peptidase I

Background

TPP1 encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

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Bioinformatics

Gene Symbol TPP1