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TNF RII/TNFRSF1B Antibody (TR75-54)

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Product Details

Summary
Product Discontinued
View other related TNF RII/TNFRSF1B Primary Antibodies

Order Details


    • Catalog Number
      NBP1-43357
    • Availability
      Product Discontinued

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TNF RII/TNFRSF1B Antibody (TR75-54) Summary

Immunogen
The immunogen for this antibody was TNFR2p75.
Isotype
IgG
Clonality
Monoclonal
Host
Armenian Hamster
Gene
TNFRSF1B
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Immunoprecipitation
  • Western Blot
Application Notes
The TR75-54 antibody has been tested as the capture antibody in a sandwich ELISA for analysis of mouse TNFRII in combination with the biotin TR75-32 antibody for detection and recombinant mouse TNFRII as the standard. A suitable range of concentrations of this antibody for ELISA capture is 1-4 ug/ml. A standard curve consisting of doubling dilutions of the recombinant standard over the range of 1000 pg/ml - 8 pg/ml should be included in each ELISA plate.

Reactivity Notes

This antibody is reactive to Mouse.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Aqueous , may contain carrier protein/stabilizer.
Preservative
0.09% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for TNF RII/TNFRSF1B Antibody (TR75-54)

  • CD120b antigen
  • CD120b
  • Etanercept
  • p75 TNF receptor
  • p75TBPII
  • p75TNFR
  • soluble TNFR1B variant 1
  • TNF RII
  • TNFBRp80 TNF-alpha receptor
  • TNF-R2
  • TNFR2TNFR1B
  • TNF-R75
  • TNFR80
  • TNFRII
  • TNF-RII
  • TNF-R-II
  • TNFR-II
  • TNFRSF1B
  • tumor necrosis factor beta receptor
  • tumor necrosis factor binding protein 2
  • Tumor necrosis factor receptor 2
  • tumor necrosis factor receptor superfamily member 1B
  • tumor necrosis factor receptor superfamily, member 1B
  • Tumor necrosis factor receptor type II

Background

The TR75-54 monoclonal antibody reacts with mouse Tumor Necrosis Factor Receptor II (TNFRII, TNFR-p80, TNFRSF1B, CD120b). TNFRII is expressed in a variety of cell types and strongly expressed on stimulated T and B lymphocytes. TNFRII is the main TNF receptor found on circulating T cells and is the major mediator of autoregulatory apoptosis in CD8+ cells. The soluble TNF receptors are truncated forms of cell surface receptors with neutralizing activity on both TNF-alpha and TNF-beta. It has been suggested that the proinflammatory and immunosuppressive properties of TNF segregate at the level of its receptors and that the pool of TNF bound to soluble receptors could represent a reservoir to control the TNF release.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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TNF RII/TNFRSF1B
Antibody (TR75-54)
NBP1-43357
TNF RII/TNFRSF1B Antibody (TR75-54)
Species: Mu
Applications: WB, ELISA, Flow, IP

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Bioinformatics

Gene Symbol TNFRSF1B