PPAR alpha Antibody (NB100-78572)
PPAR alpha Antibody
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Distributor Data...
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anti-Peroxisome proliferator-activated receptor antibody, |
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PPAR alpha Antibody Summary: | | Gene: | PPARA |
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| Purity: | Immunogen affinity purified |
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| Host: | Rabbit |
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| | | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional PPAR alpha Products PPAR alpha Antibody Details: | Isotype: | IgG |
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| Immunogen: | Recombinant (partial), N-terminal |
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| Uses: | Each lot of this antibody is quality control tested by immunofluorescence staining. For immunofluorescence microscopy: Use a dilution range of 1:100~1:400. It is recommended that the reagent be titrated for optimal performance for each application. |
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| Dilutions: | immunofluorescence |
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| Unit Size: | 0.1 ml |
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| Concentration: | 0.5 mg/ml |
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| Positive Controls: | 1 Positive Controls |
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Packaging: | Storage: | Store at 4 °C. Do not freeze. |
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| Buffer: | PBS [pH 7.2] |
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| Preservative: | 0.09% Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: PPAR (Peroxisome proliferator activated receptor) belongs to the nuclear hormone receptor family, NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain. PPAR subfamily consists of three structurally related members, PPARa, PPARb/d, and PPARg (52 kD, 50 kD, and 58 kD, respectively). PPARa expressed in skeletal muscle, liver, heart and kidney. PPARb/d expressed in many tissues but markedly in brain, adipose tissue and skin. PPARg expressed in adipose tissue, skeletal muscle, spleen, heart, liver, placenta, lung and ovary. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. PPARa controls expression of genes implicated in lipid metabolism. PPARb/d stimulates fatty acid oxidation predominantly acting in muscle. PPARg is a key regulator of glucose homeostasis and adipogenesis. PPARs also plays an important role in controlling immune and inflammatory responses. The poly6371 antibody recognizes human PPAR a, b/d, and g isoforms and has been shown to be useful for immunoflorence staining.
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Images (1) Reviews (0) Related Products (23) Exploring PPAR alpha Working with PPAR alpha
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Jump to: Publications, Images, Ask a Question
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Working with PPAR alpha
PPAR alpha Antibody Images (1) Immunofluorescent: PPAR Antibody [NB100-78572] - Immunofluorescent microscope analysis of Hela cells using anti-PPAR polyclonal antibody Poly6371 (red) and a-tubulin (clone 10D8, green). Nuclei are stained with DAPI (blue). |
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Publications (3)PPAR alpha Antibody Background References:- Kersten, S., et al. 2000. Nature 405: 421
- Lee, C.-H., 2006. Proc. Nat. Acad. Sci. 103: 3444
more... - Fu, J., et al. 2003. Nature 425: 90
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Jump to: Positive Controls, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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Related ProductsPositive Controls| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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Other Positive Controls- PPAR alpha expressed in skeletal muscle, liver, heart and kidney. PPAR beta/ delta expressed in many
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Lysates (3)Peptides and ProteinsPrimary Antibodies (14)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| PPAR alpha Antibody | NB600-636 | Bv, Ca, Ha, Mu, Rt | ELISA, IHC-P, WB | (3) | | | | | PPAR alpha Antibody | NBP1-61646 | Hu, Mu, Rt | ELISA, IF, WB | (2) | | | | | PPAR alpha Antibody | PAB11321 | Bv, Ca, Ha, Hu, Mk, Mu, Po, Rt | ELISA, WB | | | | | | PPAR alpha Antibody (3B6/PPAR) | NB300-537 | Hu, Mu, Rt | GS, IP, WB | | (3) | | | | PPAR alpha Antibody | H00005465-B01 | Hu | ELISA, IF, WB | (2) | | | | | ... and 9 more. See All » |
RNAi (5)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Rabbit IgG Antibody [HRP] | NB730-H | Rb | ELISA, ICC, IHC-P, WB | | (5) | | | | Rabbit IgG Antibody [FITC] | NB730-F | Rb | ICC, IHC-P | | (1) | | | | Rabbit IgG Antibody [Biotin] | NB730-B | Rb | ELISA, ICC, IHC-P, WB | | | | | | Rabbit IgG, H/L Chains Antibody [DyLight 488] | NBP1-72944 | Rb | FLISA, IF, WB | (3) | | | | | Rabbit IgG Antibody [Alkaline Phosphatase] | NB730-AP | Rb | ELISA, ICC, IHC-P, WB | | (1) | | | | See All » |
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