PPAR alpha Antibody (NB100-78572)

PPAR alpha Antibody (NB100-78572) (0.1 ml)

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	Catalog Number	NB100-78572
	Size(s)	0.1 ml	Price: N/A
	Availability	Discontinued
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anti-PPARalpha antibody, anti-Nuclear receptor subfamily 1 group C member 1 antibody, anti-alpha antibody, anti-hPPAR antibody, anti-PPARMGC2452 antibody, anti-NR1C1MGC2237 antibody, anti-PPAR-alpha antibody, anti-peroxisome proliferator-activated receptor alpha antibody

PPAR alpha Antibody Summary:

Species:	Hu	Gene:	PPARA
Applications:	IF	Purity:	Immunogen affinity purified
Clonality:	Polyclonal	Host:	Rabbit
Specificity:	PPAR
Publications:	NB100-78572 has at least 3 Background References

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PPAR alpha Antibody Details:

Isotype:	IgG
Immunogen:	Recombinant (partial), N-terminal

Species Reactivity:

Human.

Applications:

Uses:	Each lot of this antibody is quality control tested by immunofluorescence staining. For immunofluorescence microscopy: Use a dilution range of 1:100~1:400. It is recommended that the reagent be titrated for optimal performance for each application.
Dilutions:	immunofluorescence
Unit Size:	0.1 ml
Concentration:	0.5 mg/ml
Positive Controls:	1 Positive Controls

Packaging:

Storage:	Store at 4°C. Do not freeze.
Buffer:	PBS [pH 7.2]
Preservative:	0.09% Sodium Azide
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.

Gene Symbol: PPARA

Entrez:	5465 (Human)

Related Genes:

Background:

PPAR (Peroxisome proliferator activated receptor) belongs to the nuclear hormone receptor family, NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain. PPAR subfamily consists of three structurally related members, PPARa, PPARb/d, and PPARg (52 kD, 50 kD, and 58 kD, respectively). PPARa expressed in skeletal muscle, liver, heart and kidney. PPARb/d expressed in many tissues but markedly in brain, adipose tissue and skin. PPARg expressed in adipose tissue, skeletal muscle, spleen, heart, liver, placenta, lung and ovary. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. PPARa controls expression of genes implicated in lipid metabolism. PPARb/d stimulates fatty acid oxidation predominantly acting in muscle. PPARg is a key regulator of glucose homeostasis and adipogenesis. PPARs also plays an important role in controlling immune and inflammatory responses. The poly6371 antibody recognizes human PPAR a, b/d, and g isoforms and has been shown to be useful for immunoflorence staining.

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PPAR alpha Antibody Images (1)

	Immunofluorescent: PPAR Antibody [NB100-78572] - Immunofluorescent microscope analysis of Hela cells using anti-PPAR polyclonal antibody Poly6371 (red) and a-tubulin (clone 10D8, green). Nuclei are stained with DAPI (blue).