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FACA/FANCA Antibody (5G9) [DyLight 550]

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-18973R
    • Availability
      Product Discontinued

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FACA/FANCA Antibody (5G9) [DyLight 550] Summary

Immunogen
A synthetic peptide made to a C-terminal region of human FANCA (within amino acids 1380-1455) [Swiss-Prot #O15360].
Localization
Nucleus. Cytoplasm. Note= The major form is nuclear. The minor form is cytoplasmic.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
FANCA
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunoprecipitation
  • Western Blot
Application Notes
This FANCA antibody is useful for Immunoprecipitation and Western Blot, where a band is seen ~163 kDa. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
163 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for FACA/FANCA Antibody (5G9) [DyLight 550]

  • FA
  • FA1
  • FAA
  • FAAMGC75158
  • FACA
  • FACAFanconi anemia group A protein
  • FAH
  • FA-H
  • FANCA
  • FANCH
  • Fanconi anemia, complementation group A
  • Fanconi anemia, complementation group H
  • Fanconi anemia, type 1
  • Protein FACA

Background

Faconi Anemia Group A Protein is a DNA repair protein. It may function as a cell cycle checkpoint or in post replication repair. FANCA may be important for the maintenance of chromosome stability and reparation of interstrand DNA cross linkages. Defects in this protein result in a disease state, Fanconi anemia, an autosomal recessive disorder. Fanconi anemia results in may congenital malformations and predisposition to malignant formations.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol FANCA