FACA/FANCA Antibody (5G9) [Biotin] Summary
| Immunogen |
A synthetic peptide made to a C-terminal region of human FANCA (within amino acids 1380-1455) [Swiss-Prot #O15360]. |
| Localization |
Nucleus. Cytoplasm. Note= The major form is nuclear. The minor form is cytoplasmic. |
| Isotype |
IgG1 |
| Clonality |
Monoclonal |
| Host |
Mouse |
| Gene |
FANCA |
| Purity |
Protein G purified |
| Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
| Dilutions |
- Immunoprecipitation
- Western Blot
|
| Application Notes |
This FANCA antibody is useful for Immunoprecipitation and Western Blot, where a band is seen ~163 kDa. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
| Theoretical MW |
163 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
| Readout System |
|
Reactivity Notes
Packaging, Storage & Formulations
| Storage |
Store at 4C in the dark. |
| Buffer |
PBS |
| Preservative |
0.05% Sodium Azide |
| Purity |
Protein G purified |
Alternate Names for FACA/FANCA Antibody (5G9) [Biotin]
Background
Faconi Anemia Group A Protein is a DNA repair protein. It may function as a cell cycle checkpoint or in post replication repair. FANCA may be important for the maintenance of chromosome stability and reparation of interstrand DNA cross linkages. Defects in this protein result in a disease state, Fanconi anemia, an autosomal recessive disorder. Fanconi anemia results in may congenital malformations and predisposition to malignant formations.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Secondary Antibodies
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