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Synaptojanin 1 Antibody (AC1) [DyLight 650]

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB300-428C
    • Availability
      Product Discontinued

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Synaptojanin 1 Antibody (AC1) [DyLight 650] Summary

Immunogen
Recombinant fragment, corresponding to C-terminal amino acids 1156-1286 (proline-rich domain) of rat Synaptojanin I. [UniProt# Q62910]
Localization
Cytoplasmic
Specificity
This is specific for the rat 145 and 170 KD proteins only.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
SYNJ1
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Electron Microscopy
  • Immunocytochemistry/ Immunofluorescence
  • Immunoprecipitation
  • Western Blot
Application Notes
This Synaptojanin 1 (AC1) antibody works in Immunocytochemistry/Immunofluorescence, Immunoprecipitation and Western blot. Electron Microscopy was reported in scientific literature. In WB it detects bands of approximately 145 and 170 kDa. The 145 kDa isoform is predominantly expressed in the nervous system.

Reactivity Notes

Rat. Human reactivity is very weak. Does not react with any other species, including mouse. mouse reactivity reported in scientific literature (PMID: 24052255)

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Synaptojanin 1 Antibody (AC1) [DyLight 650]

  • EC 3.1.3
  • EC 3.1.3.36
  • KIAA0910
  • polyphosphoinositide phosphatase, 10synaptojanin-1
  • Synaptic inositol-14,5-trisphosphate 5-phosphatase 1
  • synaptojanin 1

Background

Synaptojanin 1 [formerly known as synaptojanin] is an inositol 5-phosphatase which exists in two tissue specific isoforms (170 and 145 kDa). Synaptojanin is involved in clathrin-mediated endocytosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SYNJ1