NB100-63193 detects an epitope corresponding to 429-442aa of human LXR (liver X receptor) alpha and to 443-456aa of human LXR beta. LXR alpha and beta are members of the nuclear hormone receptor superfamily of ligand-activated transcription factors, and each have a molecular weight of 55kD. LXR alpha and beta are sterol-responsive with the ability to directly bind several oxysterol metabolites. Many LXR target genes have been identified that implicate these receptors in a variety of physiological processes including cholesterol transport and metabolism, glucose metabolism, and inflammation.
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
Peptide sequence CRLQDKKLPPLLSEI corresponding to the internal region of LXR Alpha/Beta.
Localization:
Nuclear
Species Reactivity:
Human. Not yet tested in other species.
Applications:
Uses:
This antibody is useful for ELISA, Western Blot
Dilutions:
ELISA
Western Blot
Unit Size:
0.1 mg
Concentration:
0.5 mg/ml
Packaging:
Storage:
Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles.
Preservative:
0.02% Sodium Azide
Limitations:
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.