| Immunogen | Peptide sequence CRLQDKKLPPLLSEI corresponding to the internal region of LXR Alpha/Beta. |
| Localization | Nuclear |
| Specificity | NB100-63193 detects an epitope corresponding to 429-442aa of human LXR (liver X receptor) alpha and to 443-456aa of human LXR beta. LXR alpha and beta are members of the nuclear hormone receptor superfamily of ligand-activated transcription factors, and each have a molecular weight of 55kD. LXR alpha and beta are sterol-responsive with the ability to directly bind several oxysterol metabolites. Many LXR target genes have been identified that implicate these receptors in a variety of physiological processes including cholesterol transport and metabolism, glucose metabolism, and inflammation. |
| Isotype | IgG |
| Clonality | Polyclonal |
| Host | Goat |
| Gene | NR1H3 |
| Purity | Immunogen affinity purified |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
| Storage | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Buffer | TRIS Buffered Saline & 0.5%BSA |
| Preservative | 0.02% Sodium Azide |
| Concentration | 0.5 mg/ml |
| Purity | Immunogen affinity purified |
Secondary Antibodies |
Isotype Controls |
Research Areas for LXR alpha/NR1H3 Antibody (NB100-63193)Find related products by research area.
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