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HDAC3 Antibody (EP462Y)

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB100-79966
    • Availability
      Product Discontinued

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HDAC3 Antibody (EP462Y) Summary

Immunogen
A synthetic peptide corresponding to residues near the N-terminus of Histone deacetylase 3 was used as an immunogen.
Epitope
(N-term)
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
HDAC3
Purity
Tissue culture supernatant
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:100
  • Immunohistochemistry 1:100-250
  • Immunohistochemistry-Paraffin 1:100-250
  • Western Blot 1:1000-2000
Theoretical MW
49 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Reacts with: Mouse, Rat, Human

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
49% PBS, 0.05% BSA and 50% Glycerol
Preservative
0.01% Sodium Azide
Purity
Tissue culture supernatant

Notes

Produced using Abcam's RabMab® technology. RabMab® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

Alternate Names for HDAC3 Antibody (EP462Y)

  • EC 3.5.1.98
  • HD3RPD3-2RPD3
  • HDAC3
  • Histone Deacetylase 3
  • KDAC3
  • RPD3-2
  • SMAP45

Background

Histone deacetylase 3 belongs to the histone deacetylase family type 1 which actively deacetylate Histones. Currently 3 known isoforms exists (HDAC3, HDAC3A and HDAC3C) (1). HDAC3 represses transcription and binds transcription factor YY1 to form a large complex. N-Cor binds HDAC3 in a different manner than other HDACs. In addition to N-Cor, HDAC3 will form a complex with corepressor SMRT (2). HDAC3 is also known to interact with DAXX, HDAC10 and DACH1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Bioinformatics

Gene Symbol HDAC3
Entrez
Uniprot