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Clonality:	Monoclonal
Specificity:	ACTL6A - actin-like 6A (3C4)
Purity:	IgG purified
Host:	Mouse

Immunogen:	ACTL6A (NP_817126, 1 a.a. ~ 81 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Epitope:	MVVERDDGSTLMEIDGDKGKQGGPTY YIDTNALRVPRENMEAISPLKNGMVE DWDSFQAILDHTYKMHVKSEASLHPV LM*
Clone:	3C4
Isotype:	IgG1 Kappa

Entrez:	86 (Human)
Swiss Prot:	NP_817126 (Human)

This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described.

	Human
Reactivity:	Human..
*Note not all species have been tested for reactivity. Only those species listed have been tested. We cannot make any guarantees about additional reactivities or cross reactivities beyond those that have been tested. This antibody may or may not react with other species.

	WB, ELISA
Uses:	Antibody Reactive Against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.
Dilutions:	ELISA, Western Blot 1:500

Storage:	Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer:	In 1x PBS, pH 7.2
Preservative:	No Preservative
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Images (1)

Detection limit for recombinant GST tagged ACTL6A is approximately 0.3ng/ml as a capture antibody.

1 Antibody Pairs

2 Lysates

5 Peptides and Proteins

6 Primary Antibodies

3 RNAi

216 Secondary Antibodies

SMARCA1, ARFRP1, ACTL6B, SMARCA4, KAP, VCSA1, MANF, RERE, CRISP1, AKR1B10, ANGPTL4, SMARCA2, BANF1, TRRAP, ACTR1A, HIST1H4F, HIST2H4A, HIST1H4B, HIST1H4D, INO80, HIST1H4I, HIST1H4L, HIST4H4, C4BP, HIST2H4B, HIST1H4A, HIST1H4C, HIST1H4E, RUVBL2, HIST1H4K, HIST1H4J, APOBEC3D, HIST1H4H, SMARCB1, RUVBL1, APOBEC2, ACT1, PITX2, ACTR3B, KAT5