Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
The epitope recognized by this antibody maps to a region between residue 2462 and 2511 of human fatty acid synthase using the numbering given in entry NP_004095.4 (GeneID 2194).
Species Reactivity:
Human.
Applications:
Uses:
Western Blot and Immunoprecipitation
Dilutions:
immunoprecipitation 2-5 ug/mg lysate,
Western Blot 1:2000-1:10000
Unit Size:
0.02 mg
Concentration:
0.2 mg/ml
Packaging:
Storage:
Store at 4 °C. Do not freeze.
Buffer:
Tris-buffered Saline containing 0.1% BSA
Preservative:
0.09% Sodium Azide
Limitations:
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.
Western Blot and Immunoprecipitation: FAS Antibody [NB100-61047] -Detection of Human FAS on HeLa whole cell lysate using NB100-61047. FAS was also immunoprecipitated by rabbit anti-FAS antibody NB100-61046.