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FOXO3 [p Ser253] Antibody

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Product Details

Summary
Product Discontinued
View other related FOXO3 Primary Antibodies

Order Details


    • Catalog Number
      NBP1-19927
    • Availability
      Product Discontinued

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FOXO3 [p Ser253] Antibody Summary

Immunogen
Synthetic phosphopeptide derived from human FOXO3A around the phosphorylation site of Serine 253.
Modification
p Ser253
Clonality
Polyclonal
Host
Rabbit
Gene
FOXO3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50-1:200
  • Immunohistochemistry-Paraffin 1:50-1:200
  • Western Blot 1:500-1:1000
Application Notes
Western blot (WB) analysis of p-FOXO3A (S253) pAb in extracts from NIH/3T3 cells .
Immunohistochemistry (IHC) analyzes of p-FOXO3A (S253) pAb in paraffin-embedded human breast carcinoma tissue.
Theoretical MW
97 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Reviewed Applications
Read 3 Reviews rated 3.7
using
NBP1-19927 in the following applications:

Publications
Read Publications using
NBP1-19927 in the following applications:

  • WB
    1 publication

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for FOXO3 [p Ser253] Antibody

  • AF6q21 protein
  • AF6q21
  • DKFZp781A0677
  • FKHRL1
  • FKHRL1MGC31925
  • FKHRL1P2
  • forkhead box O3
  • forkhead box protein O3
  • forkhead homolog (rhabdomyosarcoma) like 1
  • Forkhead in rhabdomyosarcoma-like 1
  • forkhead, Drosophila, homolog of, in rhabdomyosarcoma-like 1
  • FOXO2
  • FoxO3
  • FOXO3A
  • FOXO3Aforkhead box O3A
  • MGC12739

Background

FOXO3A belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. Forkhead transcription factors of the FoxO subfamily are emerging as a shared component among pathways regulating diverse cellular functions, such as differentiation, metabolism, proliferation, and survival. Their transcriptional output is controlled via a two-tiered mechanism of phosphorylation and acetylation.FOXO3A is a transcriptional activator which triggers apoptosis in the absence of survival factors. It recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. FOXO3a has been shown to induce cell growth arrest to effect tumor suppression and FOXO3A genotype is strongly associated with human longevity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for FOXO3 Antibody (NBP1-19927)(2)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.


Filter By Application
WB
(1)
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Filter By Species
Human
(1)
All Species

Reviews for FOXO3 Antibody (NBP1-19927) (3) 3.73

Average Rating: 3.7
(Based on 3 reviews)
We have 3 reviews tested in 2 species: Human, Mouse.

Reviews using NBP1-19927:
Filter by Applications
WB
(3)
All Applications
Filter by Species
Human
(2)
Mouse
(1)
All Species
Images Ratings Applications Species Date Details
Western Blot FOXO3 NBP1-19927
Enlarge
3
reviewed by:
Youngil Lee
WB Mouse 05/06/2017
View

Summary

ApplicationWestern Blot
Sample TestedMouse skeletal muscle
SpeciesMouse
LotAA66135
Western Blot FOXO3 NBP1-19927
Enlarge
4
reviewed by:
Verified Customer
WB Human 10/04/2015
View

Summary

ApplicationWestern Blot
Sample TestedHuman cancer cell whole cell lysate
SpeciesHuman
Western Blot FOXO3 NBP1-19927
Enlarge
4
reviewed by:
Tora Henriksen
WB Human 09/18/2014
View

Summary

ApplicationWestern Blot
Sample TestedHuman primary muscle cells
SpeciesHuman
LotCA36131

Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for FOXO3 Antibody (NBP1-19927) (0)

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Recent Reviews

3.7
5
0
4
2
3
1
2
0
1
0

Youngil Lee
05/06/2017
Application: WB
Species: Mouse

Verified Customer
10/04/2015
Application: WB
Species: Human

Tora Henriksen
09/18/2014
Application: WB
Species: Human

Bioinformatics

Gene Symbol FOXO3
Entrez
Uniprot