CYP27A1 Antibody Summary
| Immunogen |
The antiserum was produced against synthesized peptide derived from human Cytochrome P450 27A1. The immunogen region is: Internal. |
| Specificity |
Cytochrome P450 27A1 Antibody detects endogenous levels of total Cytochrome P450 27A1 protein. |
| Clonality |
Polyclonal |
| Host |
Rabbit |
| Gene |
CYP27A1 |
| Purity |
Immunogen affinity purified |
| Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
| Dilutions |
- ELISA 1:10000
- Western Blot 1:500-1:1000
|
Reactivity Notes
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles. |
| Buffer |
PBS (without Mg2+ and Ca2+, pH 7.4), 0.15M NaCl and 50% Glycerol |
| Preservative |
0.02% Sodium Azide |
| Concentration |
1 mg/ml |
| Purity |
Immunogen affinity purified |
Alternate Names for CYP27A1 Antibody
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease. [provided by RefSeq]
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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