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SSEA-1 Antibody (28) [DyLight 650]

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Product Details

Summary
Product Discontinued
View other related SSEA-1 Primary Antibodies

Order Details


    • Catalog Number
      NB100-2672C
    • Availability
      Product Discontinued

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SSEA-1 Antibody (28) [DyLight 650] Summary

Immunogen
Cell preparation: Monocytes, separated from other peripheral blood leucocytes (PBL) on fibronectin plates.
Localization
Type II membrane protein. Membrane bound form in trans cisternae of Golgi.
Specificity
Specific to CD15. 28 is useful for leukaemia typing and purification of stem cells.
Isotype
IgM
Clonality
Monoclonal
Host
Mouse
Gene
FUT4
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunoprecipitation

Reactivity Notes

Cross-reacts with Human. Mouse reactivity reported in scientific literature (PMID: 29168692).

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
50mM sodium borate
Preservative
No Preservative
Purity
Protein A or G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for SSEA-1 Antibody (28) [DyLight 650]

  • alpha-(1,3)-fucosyltransferase
  • CD15
  • EC 2.4.1
  • EC 2.4.1.-
  • EC 2.4.1.65
  • ELAM-1 ligand fucosyltransferase
  • ELFT
  • FCT3AELAM ligand fucosyltransferase
  • fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
  • Fucosyltransferase 4
  • Fucosyltransferase IV
  • FUC-TIV
  • fucT-IV
  • FUTIV
  • Galactoside 3-L-fucosyltransferase
  • Lewis X
  • LeX
  • SSEA1
  • SSEA-1
  • stage-specific embryonic antigen 1

Background

The CD15 antigen is expressed on approximately 90% human circulating granulocytes (membranes and granules), 30 to 60% of circulating monocytes and is absent from normal lymphocytes. CD15 antigen is also expressed on Reed Sternberg cells of Hodgkin's disease, on T cell lymphomas including mycosis fungoides and on some leukemias. Outside the hematopoietic system, CD15 expression is described in certain normal and neoplastic epithelial cells and in astrocytes. At least 5 major CD15 antigens (105, 135, 165, 185, 220 kDa) are present on the surface membranes of polymorphonuclear cells. The hapten occurs also in glycolipids. CD15 plays a role in mediating phagocytosis, bactericidal activity and chemotaxis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol FUT4