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Blooms Syndrome Protein Blm Antibody

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Product Details

Summary
Product Discontinued
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    • Catalog Number
      NB100-1589
    • Availability
      Product Discontinued

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Blooms Syndrome Protein Blm Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residues 50 and 100 of mouse Bloom Syndrome Homolog using the numbering given in entry NP_031576.2 (GeneID 12144).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
BLM
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunoprecipitation 1-4 ug/mg of lysate
Application Notes
This antibody is useful for Immunoprecipitation. For WB use rabbit anti-BLM antibody NB 100-1590 for WB of mouse BLM.
Publications
Read Publication using NB100-1589.

Reactivity Notes

Human reactivity reported in scientific literature (PMID: 29882484).

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Blooms Syndrome Protein Blm Antibody

  • BLM
  • Bloom syndrome
  • Bloom syndrome, RecQ helicase-like
  • Blooms Syndrome Protein Blm
  • BSBloom syndrome protein
  • DNA helicase, RecQ-like type 2
  • EC 3.6.1
  • EC 3.6.4.12
  • MGC126616
  • MGC131618
  • RecQ protein-like 3
  • RecQ2
  • RECQ2MGC131620
  • RECQL3
  • RECQL3RECQL2

Background

Bloom syndrome protein (BLM) is a RecQ DNA-helicase that plays a role in DNA replication and repair. Mutations and inactivation of BLM result in human syndromes characterized by dwarfism, infertility, erythema, learning disabilities, immune deficiency and predisposition to cancer. BLM has been shown to associate with the BRCA1-associated genome surveillance complex (BASC) which contains BRCA1, MSH2, MSH6, MLH1, ATM, PMS2 and the RAD50-MRE11-NBS1 protein complex. BLM is also known as RecQ protein-like 3, DNA helicase, RecQ-like type 2, RECQ2, RECQL2, RECQL3, BS, MGC126616, MGC131618, and MGC131620.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Blooms Syndrome Protein Blm Antibody (NB100-1589)(1)

We have publications tested in 1 confirmed species: Human.


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Bioinformatics

Gene Symbol BLM
Entrez
Uniprot